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General Information

Romiplostim is indicated to treat idiopathic thrombocytopenic purpura (ITP). In which the blood does not clot properly due to a lack of platelets. Platelets are a type of blood cell needed to form blood clots and prevent bleeding. This medication decreases your risk of bleeding by increasing the number of platelets.

Idiopathic thrombocytopenic purpura is an immune disorder in which the blood does not clot normally. It may cause excessive bruising and bleeding.

How does Romiplostim work?

Romiplostim activates intracellular transcriptional pathways to increase the production of platelets. It also works similarly to thrombopoietin (TPO). It is an endogenous glycoprotein hormone that regulates the production of platelets in the bone marrow.

Why use Romiplostim?

Romiplostim is in the class of medications called thrombopoietin receptor agonists. This causes the cells in the bone to the marrow. It is to produce more platelets. This is a prescription approved by the Food and Drug Administration (FDA). Romiplostim comes as a sterile, preservative-free, lyophilized, and solid white powder for subcutaneous injection. This product is available in the strengths of 250 mg and 500 mg that contain Romiplostim as an active ingredient.

How to use Romiplostim?

The recommended dosage of Romiplostim is based on your condition and response. It is important that you used this drug exactly as it is given by your doctor. This is to be injected under the skin usually once a week. For the right dose, your doctor will order blood tests (platelet counts). Let your doctor know if you develop any bruising or bleeding.

Do not use this in a larger or smaller amount.  Take this regularly for the best benefit. If your condition does not improve, call your doctor right away.

What are the side effects of Romiplostim?

Possible side effects:

  • Muscle or joint pain
  • Headache
  • Heartburn
  • Dizziness
  • Stomach upset
  • Abdominal pain
  • Trouble sleeping or insomnia
  • Pain in your legs, shoulder, or arms
  • Nausea

If these side effects persist or worsen, call for medical assistance right away.

Warnings and Precautions

  • Before using Romiplostim, tell your doctor if you are allergic to it. Tell as well if you have any medical history, allergies, or current medications.
  • Do not share this with others even if they have the same symptoms as yours.
  • Let your doctor know if you ever had blood disorders or liver disease.
  • During pregnancy, this drug should only be used when needed.
  • If you are breastfeeding women, consult your doctor first before using.