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Raloxifene Hydrochloride

Where is Raloxifene Hydrochloride used?

Raloxifene Hydrochloride is an FDA-approved oral medication used for the treatment of bone loss called osteoporosis after menopause. This is in the class of medications called selective estrogen receptor modulators (SERMs). This medicine imitates the effects of estrogen to increase the density of bone.

How does Raloxifene Hydrochloride work?

Estrogen is the main female sex hormone. It has many actions throughout the body. Breast, tissue, and bone tissue as well as cholesterol metabolism are all affected by this hormone. Blood levels start to lessen at menopause. This also affects the tissues that are normally responsive to estrogen.

Raloxifene Hydrochloride is used to both prevent and treat osteoporosis in postmenopausal women. This acts on estrogen receptors in the bone tissue where it mimics the natural effects of estrogen. This slowly reverses the excessive breakdown of bone that happens at menopause and causes an increase in bone mineral density. Wherein, it makes the bones stronger. This medication has been shown to significantly lessen the risk of spinal fractures but not hip fractures.

How is Raloxifene Hydrochloride taken?

Raloxifene Hydrochloride is to be taken by mouth usually once a day. You may take each tablet with or without a meal. Each tablet will be taken by mouth with a full glass of water. Remember to take it at the same time and in the same way each day. Do not double the dose to make up for the missed dose. Let your doctor know if your condition does not improve or if it gets worse.

The prescribed dosage for this medication is based on your medical condition, age, and response to it. You must take the right dose, not more or less. Your doctor may give you a lower dose to start and eventually increase it.

What are the possible side effects of Raloxifene Hydrochloride?

Common side effects:

  • Dizziness
  • Headache
  • Spinning sensation
  • Nausea
  • Joint pain
  • Stomach pain
  • Vomiting
  • Runny or stuffy nose

What are the precautions in taking Raloxifene Hydrochloride?

  • Before having this treatment, tell your doctor if you ever had an allergic reaction to this drug.  This product may contain an inactive ingredient that causes an allergic reaction.
  •  While taking this medicine, the risk of a blood clot forming in the veins may be temporarily increased.
  • If you suffer an illness or condition that results in you becoming immobile for a prolonged, you should stop taking this medicine as soon as possible.
  • This prescription is not recommended for use in pregnant women or breastfeeding women.

Use this medicine with caution in:

  • Women with a history or risk of stroke or mini-stroke
  • Irregular heartbeat caused by a very rapid contraction of the top two chambers of the heart
  • Breast cancer
  • Women at risk of developing blood clots in the veins
  • Women who have had raised levels of a fat called triglycerides in their blood as a result of taking oral estrogen-based medicine

This medicine should not be used in:

  • Women with signs or symptoms of cancer of the lining of the womb
  • Severely decreased kidney function
  • Decreased liver function
  • Vaginal bleeding of unknown cause
  • Failure of the normal flow of bile from the liver to the intestines
  • Rare hereditary problems of galactose intolerance