General Information
Niraparib is used for the treatment of:
- Ovarian cancer
This type of cancer begins in the ovaries. The female reproductive system contains two ovaries one on each side of the uterus. It often does undetected until it has spread within the pelvis and abdomen.
- Fallopian tube cancer
This develops in the fallopian tubes that connect the ovaries and the uterus. It typically affects women between the ages of 50 and 60.
- Primary peritoneal cancer
This is a relatively rare cancer that develops most commonly in women. This is a close relative of epithelial ovarian cancer.
How does Niraparib work?
Niraparib blocks the action of enzymes called PARP-1 and PARP-2. In which it helps to repair damaged DNA in cells. It is when the cells divide to make new cells. By blocking PARP enzymes, the damaged DNA in cancer cells cannot be repaired. As a result, the cancer cells die.
Why use Niraparib?
Niraparib is a cancer medicine that interferes with the growth and spread of cancer cells in the body. This medication is in the class of PARP inhibitors. Niraparib is a white to off-white and non-hygroscopic crystalline solid. This comes as a capsule that contains 159.4 Niraparib and is equivalent to 100 mg free bases as the active ingredient. The Food and Drug Administration (FDA) has already approved this prescription.
How to use Niraparib?
Niraparib is to be taken by mouth as directed. This medication is usually taken once a day. You may take each dose with or without food. Swallow the capsule as a whole with a full glass of water. Do not chew or break it. Don’t forget to take it at the same time each day.
The dosage is based on your medical condition and response to the treatment. Take this regularly for the best benefit. If you vomit after taking a dose, do not take another dose at that time. Take your next dose at the regular time. Follow the instructions of your doctor very carefully.
What are the side effects of Niraparib?
- Constipation
- Nausea
- Abdominal pain
- Vomiting
- Bloating
- Diarrhea
- Heartburn
- Dry mouth
- Fatigue
- Decreased appetite
- Weakness
- Back pain
- Joint pain
- Dizziness
- Runny or stuffy nose
- Cough
- Rash
- Trouble sleeping
- Loss of appetite
- Sore throat
Warnings and Precautions
- Before taking the medicine, tell your doctor if you are allergic to it. Tell as well if you have any medical history.
- Do not increase the prescribed dose of this drug or use this more often or for longer than it is given.
- Do not receive any immunization or vaccination while having this treatment without the consent of your doctor.
- This drug may make you dizzy. Avoid using any machinery or do anything that needs your alertness.
- Keep this drug far from the reach of children.
