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Where is Metyrosine used?

Metyrosine is a medication used to treat pheochromocytoma or tumor of the adrenal gland. This is given before surgery to control the condition and also given when surgery is not possible. This drug is given to those with high blood pressure who are experiencing this condition. Metyrosine is not used for other kinds of high blood pressure. This is being used for long-term medication.

This medication belongs to the general class of medicines called antihypertensives. This decreases a certain amount of chemicals in the body. Metyrosine is supplied as capsules for oral administration. The Food and Drug Administration (FDA) has already approved this medication in 1982.

How does Metyrosine work?

Metyrosine prevents the tumor from making certain natural substances like catecholamines. Those are the ones that raise blood pressure and make the heart beat faster. Lowering the number of catecholamines lessens the risk of a very serious attack of high blood pressure or a hypertensive crisis.

How is Metyrosine taken?

Your doctor may instruct you to start at a low dose of this medication and slowly increase your dose.

The recommended initial dose of this medicine for adults and children 12 years of age and older is 250 mg to be taken four times a day. The dosage may be increased to 500 mg every day to a maximum of 4.0 g per day in divided doses. This medication should be given for at least 5-7 days. Each medicine is to be taken by mouth with a full glass of water. you may take each dose with or without a meal.

While taking this, you must get plenty of fluids and pass urine frequently to avoid kidney and bladder side effects. Use this regularly and take it exactly as it is prescribed. Do not take this medication less or more than the recommended amount by your doctor. If you missed a dose, take it right away as soon as you remember it. If you often missed a dose, call your doctor for instructions.

What are the possible side effects of Metyrosine?

  • Dizziness
  • Tiredness
  • Drowsiness
  • Dry mouth
  • Light-headedness
  • Headache
  • Vomiting
  • Stomach upset or pain
  • Diarrhea as your body adjusts to the medication

If these side effects persist or get worse, call your doctor for medical assistance.

What are the precautions in taking Metyrosine?

  • Avoid alcoholic beverages. It may increase some of the side effects of this medicine.
  • Call for medical help if there is an allergic reaction or overdose.
  • Before taking this, talk to your doctor first if you are pregnant or planning to get pregnant while having this medication. Let your doctor know if you are a breastfeeding woman.
  • Your doctor must check your progress at regular visits to make sure that this medicine is working well and to check for unwanted effects.
  • This medication may cause most people to become drowsy or less alert than they are usually. Make sure you know how you react to this medicine before you use machines, drive, or do anything else that could be dangerous if you are not alert.