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Metaglip (Glipizide and Metformin HCL)

General Information

Metaglip (Glipizide and Metformin HCL) is used in people with type 2 diabetes to control high blood sugar. It is used along with a proper diet and exercise program. It may also be used with other diabetes medication.

It helps prevent nerve problems and kidney damage when you control high blood sugar. It may also prevent loss of limbs, blindness, and sexual function problems. Proper control of diabetes may also lessen your risk of stroke or heart attack.

How does Metaglip (Glipizide and Metformin HCL) work?

Metaglip (Glipizide and Metformin HCL) lowers blood sugar severely. It is by stimulating the release of insulin from the pancreas. It is an effect dependent upon functioning beta cells in the pancreatic islets. Extrapancreatic effects may play a part in the mechanism of action of oral sulfonylurea hypoglycemic medications.

This medication helps improve glucose tolerance in patients with type 2 diabetes. It lowers both basal and postprandial plasma glucose. It also decreases hepatic glucose making and lessens intestinal absorption of glucose. It improves insulin sensitivity by increasing peripheral glucose uptake and utilization.

Why use Metaglip (Glipizide and Metformin HCL)?

Metaglip is a combination of two medications. It contains Glipizide which is an oral antihyperglycemic drug of the sulfonylurea class. It also has Metformin which is an oral biguanide anti-diabetic medication. This product comes as a tablet for oral use. It is available in a 250 mg tablet. The Food and Drug Administration (FDA) has approved this medication in 2002.

How to use Metaglip (Glipizide and Metformin HCL)?

This medication is to be taken by mouth usually once or twice a day. It is to be taken with food as direct by your doctor. Drink plenty of fluids when taking this drug.

The dosage is based on your medical condition and response. Remember to take it at the same time every day. Take each dose exactly as it is prescribed.

What are the side-effects of Metaglip (Glipizide and Metformin HCL)?

  • Nausea
  • Upset stomach
  • Diarrhea
  • Headache
  • Cold symptoms such as sneezing, sore throat, or stuffy nose

Warnings and Precautions

  • Inform your doctor if you have any medical history or current s.
  • Tell also if you have any allergies. This drug may have an inactive ingredient that causes an allergic reaction.
  • You may experience dizziness or drowsiness due to low or high blood sugar. Do not drive or use any machinery that needs your alertness. Do it until you are sure you can perform such activities safely.
  •  While taking this medication, limit alcohol. It may cause an increased risk of developing hypoglycemia and lactic acidosis.