General Information

Letermovir Tablets is used to prevent disease caused by a virus called cytomegalovirus (CMV). It usually occurs in people who have received a bone marrow transplant. CMV is a type of disease that leads to serious infections in the body.  It includes infection in the eye called CMV retinitis that may cause blindness.

How do Letermovir Tablets work?

Letermovir inhibits the activity of this complex to prevent the creation of mature viral genomes and the production of viable viral particles. This also inhibits the CMV DNA terminase complex which is required for cleavage and packaging of viral progeny DNA. Letermovir affects the production of proper unit length genomes and interferes with virion maturation. Genotypic characterization of virus resistant to this medicine confirmed that this targets the terminase complex.

Why use Letermovir Tablets?

Letermovir Tablets is an anti-viral medication that is approved by the Food and Drug Administration (FDA). This helps prevent or stop the growth of the virus that is present in your body. This medication is an inhibitor of the CMV DNA terminase complex. Letermovir is available as 240 mg and 480 mg tablets for oral use.

How to use Letermovir Tablets?

The recommended dose is based on your medical condition and response to it. Take this medication exactly as it is given by your doctor. Do not take more or less than the prescription.

Letermovir Tablets is to be taken by mouth. Usually, it is to be taken once a day. You may take each dose with or without a meal. Swallow the tablet as a whole with a full glass of water. While taking this medicine, drink plenty of fluids. For the best effect, take this regularly. Remember to take each dose at the same time every day.

What are the side effects of Letermovir Tablets?

• Diarrhea
• Nausea
• Swelling of the extremities
• Vomiting
• Fatigue
• Abdominal pain
• Cough
• Headache

Warnings and Precautions

• Before using this medication, tell your doctor if you have or have ever had kidney or liver disease.
• Let your doctor know if you are allergic to it or if you have any allergies. This drug may contain an inactive ingredient that causes an allergic reaction.
• If you missed a dose, take it as soon as you remember it. If it is almost time for your next dose, skip the missed dose and follow your regular dosing schedule.
• Keep this medication away from the reach of children. It is to keep them from any unwanted harm.