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Labetalol Hydrochloride

Labetalol Hydrochloride is used for the treatment of high blood pressure and angina pectoris. 

High blood pressure is a condition in which the long-term force of the blood against your artery walls is high enough. It may eventually cause health problems. Blood pressure is determined both by the amount of blood your heart pumps and the amount of resistance to blood flow in your arteries. The more blood your heart pumps and the narrower your arteries, the higher your blood pressure. You can have this condition for years without any symptoms. Even without symptoms, damage to blood vessels and your heart continues and can be detected. Uncontrolled high blood pressure increases your risk of serious health problems. High blood pressure usually progresses over many years and affects almost every person in time. Luckily, high blood pressure can be easily detected. And once you know you have high blood pressure, you can work with your doctor to control it. A few people with high blood pressure may have headaches, shortness of breath or nosebleeds, but these signs and symptoms aren’t specific and usually don’t occur until high blood pressure has reached a severe or life-threatening stage.

Angina pectoris is a type of chest pain caused by reduced blood flow to the heart. Angina is a symptom of coronary artery disease. This condition is often described as pressure, squeezing, heaviness, tightness, or pain in your chest. Several people with angina pectoris define it as feeling like a heavyweight has been placed on their chest or feeling like a vise is squeezing their chest. The symptoms of angina may include:

  • Pain in your arms, jaw, neck, shoulder, and back accompanying chest pain
  • Chest pain or discomfort
  • Fatigue
  • Nausea
  • Sweating
  • Shortness of breath
  • Dizziness 

Labetalol Hydrochloride is a type of medication called alpha-blocker and beta-blocker. This blocks the action of certain natural chemicals in your body. By that, it lowers the heart rate, the strain on the heart, and the blood pressure. The Food and Drug Administration (FDA) has already approved this prescription. Labetalol Hydrochloride is supplied as a tablet with the dosage strengths of 100 mg, 200 mg, and 300 mg for oral use. 

How does Labetalol Hydrochloride work?

Labetalol Hydrochloride works by blocking beta receptors that are found in several parts of the body. Blocking the beta receptors prevents the action of two hormones that are produced naturally by the body. It is called adrenaline and noradrenaline. These hormones are frequently referred to as the ‘fight or flight’ chemicals. It is because they are responsible for the body’s reaction to stressful situations. Labetalol Hydrochloride blocks beta receptors that are found in the heart. This lessens the action of noradrenaline and adrenaline on the heart. Wherein, it causes it to beat more slowly and with less force. In turn, this decreases the pressure at which the blood is pumped out of the heart and around the body. In which it helps to moderate blood pressure. 

In angina pectoris, this medication slows the rate and force of the heartbeat also decreases the energy used by the heart to pump blood around the body. This lessens the heart’s need for oxygen which means that Labetalol Hydrochloride can also be used in the management of angina. Angina is chest pain that occurs because the heart does not get enough oxygen to meet demand. This is usually a result of the hardening or narrowing of the arteries that supply blood to the heart. This medication lessens the workload of the heart and so decreases the amount of oxygen that it needs to pump blood around the body. 

How to use Labetalol Hydrochloride?

Take this medication by mouth usually twice a day. Each dose is to be swallowed as a whole with a full glass of water. You may take this with or without a meal or as directed by your doctor. The dosage is based on your medical condition and response to the treatment. To decrease your risk of side effects, your doctor may instruct you to start this at a low dose and slowly increase it. Follow the instructions of your doctor carefully. To help you remember, take it at the same time each day.

For the treatment of high blood pressure, it may take several weeks before you get the full benefit of this prescription. It is important to continue taking this even if you feel well. Most people with this type of condition do not feel sick. 

What are the side effects of Labetalol Hydrochloride?

Common side effects:

  • Tired feeling
  • Stuffy nose
  • Upset stomach
  • Nausea
  • Spinning sensation 
  • Difficulty having an orgasm 
  • Scalp tingling may occur as your body adjusts to this drug 

Call your doctor right away if you have these side effects:

  • A light-headed feeling like you might pass out 
  • Shortness of breath 
  • Swelling
  • Rapid gain weight
  • Slow heart rate or weak pule
  • Fainting 
  • Slow breathing
  • Severe headache 
  • Blurred vision 
  • Pounding in your neck or ears 
  • Liver problems (stomach pain, loss of appetite, dark urine, flu-like symptoms, or jaundice)

Warnings and Precautions 

  • This drug may cause dizziness. You should be careful when performing activities. Do not drive or operate machinery until you know how this drug affects you. 
  • If you go into hospital or to the dentist to have an operation you should tell the person treating you that you are taking this medicine. Your blood pressure may fall too low if you are given certain types of anesthetics while taking having this medication.
  • Use this with caution in people with decreased kidney or liver function, those with a history of heart failure, or in people with slowed conduction of electrical messages between the chambers of the heart. 
  • In elderly people, those with chronic obstructive pulmonary disease, poor blood circulation in the arteries of the extremities, or a history of sudden drops in blood sugar levels, this drug should also be used carefully. 
  • This drug is not recommended for use in people with uncontrolled heart failure, a very slow heart rate, a severe form of chest pain, or those with low blood pressure. 
  • Consult your doctor first if you are pregnant or breastfeeding women before taking Labetalol Hydrochloride.