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Where is Glyburide-Metformin used?

Glyburide-Metformin is a prescription medicine used in people with type 2 diabetes to control high blood sugar. This medication is used along with a proper diet and exercise program. It may also be used with other diabetes medication.  Glyburide-Metformin can also:

  • Help prevent nerve problems and kidney damage when you control high blood sugar
  • Prevent sexual function problems, blindness, and the loss of limbs

Proper control of diabetes may also lessen your risk of heart attack and stroke. Glyburide is a second-generation oral sulfonylurea and Metformin is a type of medicine called biguanide antidiabetic agent. In the year 2000, the Food and Drug Administration (FDA) has approved this medication.

How does Glyburide-Metformin work?

Glyburide-Metforminhelps lower blood sugar levels by stimulating the release of insulin. It is the hormone accountable for regulating blood glucose. It also reduces the making of glucose in the liver and lessens the absorption of glucose by the intestines. It escalates the uptake and use of blood sugar by cells all over the body.

How is Glyburide-Metformin taken?

The dose of this medicine differs in each patient. Follow the instructions of your doctor that include only the average doses of this prescription. If your dosage is not the same as others, you should not change it apart from what your doctor tells you to do otherwise. The amount of drug you will be taking depends on the strength of the medicine. Additionally, the total doses you take every day depend on the medical condition you are treating.

Depending on your blood sugar levels, your dose daily might need to be increased. Your doctor’s physician will do this slowly and usually increase your dose by one 2.5 mg tablet each week. Your doctor will probably start you on a low dose and gradually increase your dose. Monitor your blood glucose closely. Diabetes treatment is usually life-long. Continue to take your prescription unless your doctor tells you to do otherwise.

What are the possible side effects of Glyburide-Metformin?

  • Vomiting
  • Nausea
  • Diarrhea
  • Stomach upset
  • Weight gain
  • Headache
  • Gas
  • Dizziness

What are the precautions in using Glyburide-Metformin?

  • Tell your doctor if you have ever had liver disease and heart attack or disease.
  • Talk with your doctor first before taking the drug if you are pregnant.
  • Inform your doctor if you eat less or exercise more than usual. This might affect your blood sugar. Your doctor will give you instructions if this occurs.
  • Do not take this medication if you are allergic to it or if you have severe kidney disease.
  • Do not take it twice the prescribed dosage.
  • Avoid drinking alcohol. It may lower your blood sugar and may increase your risk of lactic acidosis.
  • You should not breastfeed while taking this medicine.
  • If you a driver, you need to take extra care. Your ability to concentrate might be affected if your diabetes is not well controlled.
  • If you pass urine more often than usual or get unusually thirsty, you must let your healthcare provider know. These signs might be that there is too much sugar in your blood and there’s a need for adjustment in your treatment.
  • You should not take this drug along with Bosentan and make sure your doctor knows about all other medicines you are using for diabetes.
  • High blood sugar might occur if you do not take enough of your medicine or do not follow your meal plan. This can be serious and must be treated right away.