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Gefitinib Tablets

General Information

Gefitinib is also known for its brand name Iressa. This medicine is a treatment for lung cancer. This type of condition is the number one cause of cancer deaths. There are two types of lung cancer that grow and spreads in different ways. These are called:

  • Small-cell lung cancer (SCLC)
  • Non-small cell lung cancers (NSCLC)

Gefitinib blocks a certain protein which is an enzyme called tyrosine kinase.

How do Gefitinib Tablets work?

Gefitinib works by interfering with the pathways that signal certain cancer cells to grow.

Various cancer cells have structures called epidermal growth factor receptors (EGFRs) on their surfaces. These receptors let a protein called epidermal growth factor (EGF) to attach to the cells. When EGF attaches to the receptor, it activates an enzyme in the cell called tyrosine kinase. This enzyme activates chemical processes inside the cancer cells that make the cells develop and increase.

Gefitinib attaches to and blocks the EGF receptors on the cancer cells. This stops the EGF from activating them. This drug also stops cancer cells from growing and multiplying.  

Why use Gefitinib Tablets?

Gefitinib is the active ingredient of Iressa. This is a type of drug known as a protein kinase inhibitor. Each tablet contains 250 mg of Gefitinib. It is available as brown film-coated tablets for oral use. The Food and Drug Administration (FDA) has already approved this prescription.

How to use Gefitinib Tablets?

This medicine is to be taken by mouth with a full glass of water. It is usually taken once daily. You may take each dose with or without a meal. Remember to take it at the same time and in the same way each day.

The recommended dosage is based on your medical condition and response. Take it exactly as it is prescribed. Let your doctor know if your condition does not improve or if it worsens.

What are the side-effects of Gefitinib Tablets?

  • Diarrhea
  • Vomiting
  • Skin reactions
  • Nail disorders
  • Decreased appetite
  • Inflammation of the mouth lining
  • Dry eyes
  • Eyelid swelling

Warnings and Precautions

  • Let your doctor know if you have any medical history or current medications.
  • Do not increase the dosage or change the dosing schedule without consulting your doctor first.
  • This medicine may contain an inactive ingredient that might cause an allergic reaction. Tell your doctor if you have any allergies.
  • If you are pregnant or breastfeeding women, consult your doctor first.
  • Keep this at a dry and clean place.