General Information
Gablofen (Baclofen) Injection is used to treat muscle spasms. It happens due to certain conditions such as:
- Cerebral palsy
- Multiple sclerosis
- Spinal cord injury or disease
This medication helps to relax the muscle. This injection is used by patients who do not respond or who cannot tolerate the side effects of it.
How does Gablofen (Baclofen) Injection work?
Gablofen (Baclofen) Injection is an effective and widely used antispastic agent with a spinal site of action. This drug has central sites of action that is shown by its adverse event profile and general CNS depressant properties. GABA-B receptors interact with signal transduction pathways and neurotransmitter systems. It exerts an antinociceptive effect.
This medication depresses monosynaptic and polysynaptic reflex transmission. It is by various actions and possibly including the stimulation of GABA receptors.
This stimulation results in the inhibition of excitatory neurotransmitter release which may normally contribute to pain and spasticity
Why use Gablofen (Baclofen) Injection?
Gablofen Injection is a muscle relaxant and antispastic. It contains Baclofen as an active ingredient. It is in the class of gamma-aminobutyric acid (GABA) ergic agonist. It is a white to off-white, odorless or practically odorless crystalline powder. The Food and Drug Administration (FDA) has already approved this medication.
How to use Gablofen (Baclofen) Injection?
Gablofen (Baclofen) Injection is to be given into the space around the spinal cord or intrathecally. It is usually given using a drug pump implanted under your skin.
The dosage is based on your medical condition and response. Do not suddenly stop the medication without consulting your doctor. It may cause a serious withdrawal symptom. To prevent withdrawal symptoms, your doctor may lower your dose.
Remember to take it at the same time every day. Take it exactly as it is prescribed.
What are the side-effects of Gablofen (Baclofen) Injection?
- Drowsiness
- Sleepiness
- Nausea
- Dizziness
- Low blood pressure
- Vomiting
- Headache
- Low muscle tone
- Weakness
- Convulsions
- Seizures
- Constipation
- Chills
- Agitation
- Trouble sleeping
Warnings and Precautions
- Inform your doctor if you are allergic to it or if you have any allergies before taking this medication. This drug may have an inactive ingredient that causes an allergic reaction.
- Let your doctor know if you have any medical history or current treatments or medications.
- Do not use this past the expiration date.
- This may not be given or prescribed for pregnant or breastfeeding women.
- Keep this far from the reach of children or pets.
