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Firdapse (Amifampridine)

General Information

Firdapse (Amifampridine) is used for the treatment of Lambert-Eaton syndrome. It is a type of disorder that affects the nerves and muscles. It attacks the body’s own tissues. It interferes with the ability of nerve cells to send signals to muscle cells. This condition results in muscle weakness.

This medication can help reduce symptoms of muscle weakness. It may also help lessen the loss of movement caused by Lambert-Eaton syndrome.

How does Firdapse (Amifampridine) work?

For muscles to bond, nerves have to transfer electrical impulses to the muscles. It is through a chemical messenger called acetylcholine. It is released from the nerve endings during a period of ‘depolarisation’. It (depolarisation) refers to a sudden change in membrane potential.

Firdapse (Amifampridine) prevents charged potassium particles from leaving the nerve cells. It delays the period of depolarisation, allowing more time for the nerves to release acetylcholine. By that, it stimulates the muscles to contract.

Why use Firdapse (Amifampridine)?

Firdapse (Amifampridine) is a broad spectrum of potassium channel blocker. This drug contains Amifampridine as an active ingredient. This comes as a tablet for oral administration. Each tablet has a strength of 10 mg and is equivalent to 18.98 mg of Amifampridine. The Food and Drug Administration (FDA) has approved his medication in 2018.

How to use Firdapse (Amifampridine)?

Firdapse (Amifampridine) is to be taken by mouth usually 3 to 4 times a day. You may take it with or without food. Take it with a full glass of water. Swallow the tablet as a whole do not chew or break it.

Remember to take it at the same time each day. The recommended dosage is based on your condition and response to the treatment. Continue taking the tablet until the prescription is finished. Stopping the medication suddenly may result in a return of the infection.

What are the side-effects of Firdapse (Amifampridine)?

  • Diarrhea
  • Nausea
  • Abdominal pain
  • Back pain
  • Headache
  • Weakness
  • Dizziness
  • Constipation
  • Muscle spasms
  • Numbness and tingling

Warnings and Precautions

  • Before taking this medication, tell your doctor if you are allergic to it. Tell also if you have any allergies. This drug may have an inactive ingredient that causes an allergic reaction.
  • Do not share this with others who have the same symptoms as yours.
  • This may be prescribed for pregnant or breastfeeding women.
  • Avoid driving or using any machinery. This drug may make you feel dizzy.
  • Keep this at a dry and clean place away from the heat and moisture.