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What condition does Exenatide treat?

Exenatide is a diabetes medication used along with a proper diet and exercise to control high blood sugar. This is usually recommended in people with type 2 diabetes. Exenatide is an FDA-approved injectable medication that reduces the level of glucose in the blood.

Proper control of blood sugar levels may lessen your risk of:

  • Stroke
  • Heart attack
  • Nerve problems
  • Blindness
  • Kidney damage

How does Exenatide work?

Exenatide is a type of medicine called an incretin mimetic that works by imitating the actions of GLP-1 or glucagon-like peptide-1. These are hormones usually produced naturally by the body in response to food intake.

GLP-1 has several main actions to help control blood sugar levels:

  • It stimulates the pancreas to make insulin in response to increasing levels of glucose in the blood.
  • It lessens the production of glucagon. Glucagon is a hormone that usually increases the production of glucose by the liver.
  • It decreases the rate at which food passes from the stomach into the intestines which slow down the absorption of glucose from the gut into the bloodstream.
  • It acts on the brain to cause a sense of fullness that decreases further food consumption.

By imitating these actions of GLP-1, this medicine helps to control blood sugar levels in people with type 2 diabetes.

What is the recommended dosage for Exenatide?

This is usually used twice a day to be injected under the skin in the upper arm or thigh. The treatment should be done within 60 minutes before morning and evening meals. It may also be before the two main meals of the day at least 6 hours apart.

Clean the injection site first with rubbing alcohol before injecting each dose. The injection site must be changed each time to lessen the injury under the skin. The dosage is based on your condition and response to the treatment.

This medication should not be administered after meals. If you missed a dose, continue with your usual dose. Do not take two doses or increase the amount of your next dosage.

What are the side effects of Exenatide?

  • Vomiting
  • Nausea
  • Upset stomach
  • Constipation
  • Diarrhea
  • Loss of appetite
  • Weight loss
  • Dizziness
  • Heartburn
  • Headache

Call for medical help if there are signs of an allergic reaction:

  • Difficulty breathing
  • Hives
  • Swelling of your throat, face, tongue, or lips

What are the precautions in using Exenatide?

  • While taking this medication, carefully follow your diabetes management plan. It includes your medication, diet, exercise.
  • Do not share your pen device with others, even if the needle is changed.
  • You may experience dizziness, blurred vision, or headache due to extremely low or high blood sugar. Avoid driving or using any machinery that needs your alertness.
  • Let your doctor know if you are allergic to it or you have any other allergies.
  • Rare cases of pancreatitis have been reported in people using this medication. For this reason, you must let your doctor know if you experience unexplained persistent severe abdominal pain while using this medication, so this can be examined.
  • Keep this away from the reach of children.