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What condition does Doxercalciferol treat?

Doxercalciferol is used in people with serious kidney disease. This prescription is usually recommended for those who have high levels of a certain natural substance called parathyroid hormone (PTH). PTH is a type of hormone that your body normally produces. High levels of PTH may affect the balance of other minerals in your body. It may result in weak bones.

This drug is a man-made form of vitamin D. It helps to lessen the levels of PTH and increases calcium/phosphorus levels. This product is supplied as capsules for oral use. The Food and Drug Administration (FDA) has already approved this medication.

How does Doxercalciferol work?

Doxercalciferol acts straight on bone cells to stimulate skeletal growth. It also acts on the parathyroid glands to suppress PTH secretion and synthesis. These functions are mediated by the interaction of these biologically active metabolites. It is with specific receptor proteins in the various target tissues.

In patients with kidney disease, deficient production of biologically active vitamin D metabolites leads to secondary hyperparathyroidism. It contributes to the development of metabolic bone disease.

What is the recommended dosage for Doxercalciferol?

The recommended dosage is based on your medical condition and response to it. It is important to take it exactly as it is prescribed. Remember to take it in the same way and at the same time each day.

This medicine is to be taken by mouth usually 3 times a week. You may take each dose with or without food. Take this medicine regularly to get the most benefit from it.

It is very important to follow the diet recommended by your doctor to get the most benefit from this medication and to prevent serious side effects. Do not take more than 2 grams of calcium a day while you are taking this medication. Sources of calcium include your diet, calcium supplements, or phosphate binders. If you have any questions about how much calcium you take in a day, ask your doctor. Do not take other vitamins or supplements unless otherwise directed by your doctor.

What are the side effects of Doxercalciferol?

Common side effects:

  • Dizziness
  • Headache
  • Vomiting
  • Nausea
  • Feeling short of breath
  • General ill feeling
  • Swelling

Stop using the drug and call your doctor right away if these occur:

  • Loss of appetite
  • Weight loss
  • Increased thirst or urination
  • Lack of energy or tired feeling
  • Ringing in your ears
  • Muscle weakness
  • Feeling nervous or irritable

What are the precautions in taking Doxercalciferol?

  • Do not increase your dose or take it more frequently without the permission of your doctor.
  • You should not take other supplements or vitamins unless it is directed by your doctor.
  • Tell your doctor if you are pregnant before taking this medicine.
  • It is not known if it passes into breast milk. Talk to your doctor first before breastfeeding.
  • Tell your doctor if you are being treated for dialysis or taking antacids containing magnesium. Your doctor will probably tell you not to take these antacids during your treatment with this medicine.