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Diprolene AF (Betamethasone) Cream 0.05%

General Information

Diprolene AF (Betamethasone) Cream is indicated to treat a variety of skin conditions such as:

  • Dermatitis
  • Eczema
  • Allergies
  • Rash

This treatment reduces the redness, swelling, and itching that may occur in these types of conditions. This is a strong to very strong or high- to super-high-potency corticosteroid.


How does Diprolene AF (Betamethasone) Cream work?

This medication is a glucocorticoid receptor agonist. These changes in genetic appearance once this compound binds to the GRE. The anti-inflammatory actions of corticosteroids are thought to involve phospholipase A2 inhibitory proteins and lipocortin. In which through inhibition arachidonic acid it will control the biosynthesis of leukotrienes and prostaglandins. The immune system is suppressed by corticosteroids due to a decrease in the function of the lymphatic system. It also includes the reduction in complement concentrations, immunoglobulin, and interference with antigen-antibody binding. Betamethasone binds to plasma transcortin, and it becomes active when it is not bound to transcortin.


Why use Diprolene AF (Betamethasone) Cream?

Diprolene AF Cream contains betamethasone dipropionate. It is a synthetic adrenocorticosteroid for topical use in a cream base. Betamethasone is an analog of prednisolone. It has a slight degree of mineralocorticoid activity and a high degree of corticosteroid activity. This is approved by the Food and Drug Administration (FDA).


How to use Diprolene AF (Betamethasone) Cream?

This treatment is indicated for the skin only. Wash and dry your hands before applying the medication. Clean and dry also the affected area. Put on a thin film of the cream to the affected area and gently rub in. This is usually using 1-2 times a day. Do not bandage or wrap the area. If your doctor directs you to use this treatment in the diaper area on an infant, do not use tight-fitting diapers or plastic pants.

After putting on the cream, wash your hands unless you are using this to treat the hands. Avoid getting it in the eyes when applying this near the eyes as this may get worse or cause glaucoma. Avoid also getting the cream in the nose or mouth. If you get the medication in these areas, rinse right away with plenty of water.


What are the side-effects of Diprolene AF (Betamethasone) Cream?

  • Acne
  • Skin irritation, dryness, or discoloration
  • Redness, itching, burning, stinging, or blistering of treated skin
  • Lightened color of treated skin

Stop using this medication and call your doctor if you have:

  • Slow wound healing
  • Thinning skin
  • Increased body hair
  • Blurred vision
  • Severe skin irritation where the cream was applied
  • Signs of infection (redness, warmth, swelling)

Warnings and Precautions

  • Before using this treatment, inform your doctor if you have any allergies.
  • Do not share this with others who have the same condition as yours.
  • Keep this far from moisture and heat.