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COVID-19 Symptoms
COVID-19 Symptoms

Denavir (Penciclovir) Cream

General Information

Denavir (Penciclovir) Cream is used to treat cold sores caused by the herpes simplex virus. This is used on the lips and faces of adults. This cream can speed up healing of the sores and decrease symptoms like burning, pain, and itching.

This medication does not cure herpes and it will not prevent from passing the infection to someone else. This will also not prevent future occurrences.


How does Denavir (Penciclovir) Cream work?

Denavir (Penciclovir) selectively prevents viral DNA polymerase by opposing with deoxyguanosine triphosphate. Inhibition of DNA synthesis of virus-infected cells prevents viral reproduction. In cells not infected with herpes simplex virus, DNA synthesis is unchanged. Resistant mutants of herpes simplex virus can occur from qualitative changes in DNA polymerase or viral thymidine kinase. The most usually encountered acyclovir-resistant mutants that are deficient in viral thymidine kinase are also resistant to Penciclovir.

Denavir (Penciclovir) stops the growth and development of the virus.


Why use Denavir (Penciclovir) Cream?

Denavir (Penciclovir) an antiviral agent active against herpes viruses. This belongs to the class of medications known as antivirals. This is available for topical administration as a white cream. Each gram of Denavir contains 10mg of Penciclovir. The Food and Drug Administration (FDA) approved this treatment.

How to use Denavir (Penciclovir) Cream?

Use this medication at the first sign of infection like burning, tingling, sores, or redness.

Wash your hands first with soap and water before applying the cream. Before applying the medication, clean and dry the affected areas. Apply a thin layer of cream to completely cover the area of the cold sore or the area of itching, tingling, or redness. Then rub it gently. Apply the cream every 2 hours except during sleep. It should be applied for 4 days or as directed by your doctor.

Apply this to the skin only. Do not apply in or near the eyes. This medication may irritate the eyes. If it accidentally gets into your eyes, flush it with plenty of water. You should also not apply this inside the mouth or nose.


What are the side-effects of Denavir (Penciclovir) Cream?

  • Numbness or tingling where the cream was applied
  • Headache
  • Changes in your sense of taste
  • Application site reaction (skin discoloration, redness, burning, or hives)
  • Swollen mouth or throat

Warnings and Precautions

  • Stop using this medication and call for medical assistance if there is an allergic reaction.
  • Let your doctor know if you have any medical history or current treatments.
  • Discuss with your doctor the risks and benefits of this treatment.