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Cognex (Tacrine Hydrochloride)

General Information

Cognex (Tacrine Hydrochloride) is used for the treatment of mild to moderate dementia in patients with Alzheimer’s disease like:

  • Abstract thinking
  • Impairment of memory or judgment
  • Changes in personality

This medication will not cure the disease and will not stop the disease from getting worse. Still, this treatment can improve thinking ability in some patients with this condition.


How does Cognex (Tacrine Hydrochloride) work?

Cognex (Tacrine Hydrochloride) inhibitors block the action of acetylcholinesterase. It is the enzyme accountable for the damage of acetylcholine.

Acetylcholine is one of some neurotransmitters in the brain. It is the chemicals that nerve cells use to connect with one another. Reduced levels of acetylcholine in the brain are believed to be responsible for some of the symptoms of Alzheimer’s disease. By blocking the enzyme that destroys acetylcholine, rivastigmine increases the concentration of acetylcholine in the brain. This increase is believed to be responsible for the improvement in thinking seen with Tacrine.

Why use Cognex (Tacrine Hydrochloride)?

Cognex (Tacrine Hydrochloride) is in a class of medications known as cholinesterase inhibitors. Each capsule of Cognex contains Tacrine as the hydrochloride. This medication has the strength of 10mg, 20mg, 30mg, and 40mg for oral administration. The Food and Drug Administration (FDA) approved this in the year 1993.

How to use Cognex (Tacrine Hydrochloride)?

Use Cognex (Tacrine Hydrochloride) exactly as the prescription of your doctor. The recommended dosage is based on your condition and response. The usual starting dose of this is 10 to 20mg four times a day. The maximum dose is 160 daily. This is usually taken on an empty stomach an hour before or two hours after a meal. If stomach upset occurs, you may take it with food to reduce stomach irritation. Take it on a regular schedule and at the same time each day.

What are the side-effects of Cognex (Tacrine Hydrochloride)?

  • Diarrhea, mild nausea, vomiting
  • Upset stomach, weight loss
  • Depressed mood, agitation, urinating more than usual
  • Increased sweating, skin rash
  • Runny nose, cough, fever or chills
  • Drowsiness, dizziness, tired feeling
  • Joint or muscle pain
  • Lack of coordination or weakness

Call your doctor right away if these happen:

  • Hallucinations
  • Confusion
  • Extreme or sudden changes in behavior
  • Pain or burning when you urinate
  • Stomach pain
  • Jaundice
  • Loss of appetite

Warnings and Precautions

  • Do not use this medication if you are allergic to it.
  • Let your doctor know if you have any medical history or current medications.
  • You should not stop this or change the dosage without talking to your doctor.