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Aliskiren

Where is Aliskiren used?

Aliskiren is used for the treatment of hypertension or high blood pressure. Lowering your high blood pressure helps prevent kidney problems, strokes, or heart attacks. These benefits have been seen in controlled trials of antihypertensive medications from a wide-ranging variety of pharmacologic classes. 

Aliskiren belongs to the class of medications called direct renin inhibitors. This drug helps relax the blood vessels so blood can flow more easily. The Food and Drug Administration (FDA) has approved this medication. This is the first approved drug in a new antihypertensive class.

How does Aliskiren work?

Aliskiren leads the renin inhibitors by blocking the enzyme renin from activating. It is a procedure that helps control blood pressure. Through renin inhibitors, angiotensin II receptor blockers, and ACE inhibitors all aim the same procedure that narrows blood vessels. Through this action, the blood can flow more easily and helps prevent some complications.  

How is Aliskiren taken?

The recommended dosage for this medication will depend on your:

  • Medical condition
  • Bodyweight
  • Age
  • Medical history

This medicine is usually taken once a day. Take the medicine as a whole with a full glass of water. You may take each dose with or without food. Do not take the medicine with fruit juice. Take it plain water. High-fat foods may lessen how well this drug is absorbed by the body. It is best to avoid taking the drug with a high-fat meal. Take this regularly to get the best result. Follow your doctor’s dosing instructions very carefully.

This medication needs to be taken on a long-term basis. It is important to keep taking each dose regularly to control your blood pressure. To help you remember, take each dose at the same time each day. Hypertension does not usually make you feel sick. Check your blood pressure regularly. Do not suddenly stop taking the drug unless it is directed by your doctor.

What are the possible side effects of Aliskiren?

  • Headache
  • Heartburn
  • Light-headedness
  • Upset stomach
  • Diarrhea
  • Stuffy nose
  • Cough
  • Dizziness
  • Sore throat
  • Back pain

What are the precautions in taking Aliskiren?

  • Before taking this medication, let your doctor know if you have any allergies, medical history, or you are taking any medications including herbal products, food supplements, or vitamins.
  • Consult first your doctor if you are a breastfeeding or pregnant woman.
  • Blood pressure-lowering medicines can sometimes make you feel weary or dizzy. If you are affected, it is needed to avoid performing possibly dangerous tasks such as operating machinery or driving. If you feel dizzy, this can frequently be relieved by lying down until the symptoms pass. Some dizziness might be made worse by drinking alcohol. If you often feel dizzy you must let your doctor know, as your dose of this medication may need adjusting.
  • Do not use this past the expiration date.
  • The amount of potassium in your blood and kidney function should be monitored regularly while you are taking this medication.
  • Keep this in a dry and clean place to avoid infection.
  • Keep this away from the reach of children or pets.