Sumatriptan Succinate is a medication for the treatment of migraine. This is a neurological condition that can cause multiple symptoms. It is often characterized by intense and debilitating headaches. It can last for hours to days band the pain can be so severe that it interferes with your daily activities. Migraine often runs in families and affects all ages.
Changes in the brainstem and its interactions with the trigeminal nerve which is a major pain pathway might be involved. As a result, there might be imbalances in brain chemicals including serotonin which helps regulate pain in your nervous system. There are several migraine triggers including:
- Stress (home or work)
- Hormonal changes in women (menstrual periods, menopause, or pregnancy)
- Drinks (alcohol, caffeine, or wine)
- Sensory stimuli (bright lights, loud sounds, or strong smells)
- Weather changes
- Physical factors (sexual activity)
- Medications (oral contraceptives or vasodilators)
- Food additives (sweetener aspartame or MSG)
- Foods (aged cheeses and salty or processed foods)
For many people with migraines, the auras act as a warning, telling them that a headache is soon to come. The effects of an aura can include:
- The perception of strange, sparkling or flashing lights
- Confusing thoughts or experiences
- Blind spots or blank patches in the vision
- Zig-zagging lines in the visual field
- Stiffness in the shoulders, limbs, or neck
- Difficulty speaking
- Pins and needles in an arm or leg
- Unpleasant smells
If the following symptoms are unusual for the person with migraine, they should not be ignored:
- Visual disturbance
- An unusually severe headache
- Difficulties with speech
- Loss of sensation
Sumatriptan Succinate belongs to the class of medications known as triptans. This affects a certain natural substance that causes the narrowing of blood vessels in the brain. This may also relieve pain by affecting certain nerves in the brain. The Food and Drug Administration (FDA) has already approved this prescription. Sumatriptan Succinate is a clear, sterile, and colorless to pale yellow nonpyrogenic solution for subcutaneous injection.
How does Sumatriptan Succinate work?
Migraine is thought to involve changes in the levels of chemicals in the brain. The disturbing pain of migraine headaches is an outcome of widening or swelling of the blood vessels in the brain.
Sumatriptan Succinate acts of serotonin or 5HT receptors that are established on blood vessels in the brain which causes them to narrow. It is also thought to prevent the action of the trigeminal nerve. These actions relieve the headache and other symptoms that you may get with your migraine.
Serotonin is a chemical nerve cell produce that sends signals between your nerve cells. It is found mostly in the digestive system although it’s also in blood platelets and throughout the central nervous system. Serotonin impacts every part of your body, from your emotions to your motor skills. Serotonin is considered a natural mood stabilizer. It also helps regulate your mood naturally.
How to use Sumatriptan Succinate?
This can be injected by using a needle/syringe, an auto-injector, or a needle-free device. You must learn all the preparation and usage instructions first before using this medication. If any of the information is not clear, consult your doctor first. Make sure you understand the correct technique for injection and how to properly dispose of needles, auto-injectors, needle-free devices, syringes, and unused medication.
Inject the medication just below the skin as soon as the symptoms of your migraine appear. Before injecting each dose, clean the injection site with rubbing alcohol. Your skin should be clean and dry if using a needle-free device before injecting it. This must not be injected straight into a muscle or into a vein. Also, never inject this medication through clothing.
Do not any more doses of this medication if there is no improvement in your symptoms and call your doctor. If your headache comes back or if your symptoms are only partially relieved, you can use a second injection after an hour or as given by your doctor. In 24 hours, do not use more than 12 milligrams. Do not reuse the syringe or the needle-free device. If you are using an auto-injector device, it may be re-used. The dosage of this prescription is based on your medical condition and your response to it. Do not use medications more often or for longer than directed. Let your doctor know if you need to use this more often, if it is not working well, or if your condition gets worse.
What are the side effects of Sumatriptan Succinate?
Common side effects:
- Pain or chest tightness
- Mild headache
- Pressure or heavy feeling in any part of your body
- Feeling hot or cold
- Spinning sensation
- Flushing (redness, warmth, or tingling under your skin)
Stop using Sumatriptan Succinate and call your doctor right away if these happen:
- Severe chest pain
- Shortness of breath
- Irregular heartbeats
- Sudden and severe stomach pain
- Bloody diarrhea
- Blurred vision
- Severe headache
- Pounding in your neck or ears
- High levels of serotonin in the body (fever, muscle stiffness, vomiting, diarrhea, or twitching)
- Blood circulation problems in your legs or feet (numbness or tingling, cramps, cold feeling, or burning pain)
Warnings and Precautions
- Before using this drug, tell your doctor if you are allergic to it or if you ever had an allergic reaction to it. Tell as well to your doctor if you have allergies. This drug may have an inactive ingredient that causes an allergic reaction.
- Inform your doctor if you have any medical history especially of blood circulation problems, certain types of headaches, heart problems, seizures, or stroke.
- The certain condition can increase your risk of heart problems. Let your doctor know if you have high cholesterol, high blood pressure, diabetes, or a family history of smoker or overweight.
- If you are at a high risk of heart disease, your doctor may want to check your heart before prescribing this medication.
- This drug may make you drowsy or dizzy. Do not drive or use any machinery until you know how this affects you.
- Limit as well as alcoholic beverages.
- This is not recommended for use in pregnant or breastfeeding women. If you are planning to become pregnant, consult first your doctor.